FIPV Ab Test

Feline Infectious Peritonitis Antibody Rapid Test (FIPV Ab)

Catalog No.: JCA121C

Product Information

¤  INTENDED USE

The Feline FIPV Ab Test(FIPV Ab test) is a lateral flow immunochromatographic assay for the qualitative detection of feline infectious peritonitis antibody (FIPV Ab) in cat's  ascites or pleural fluid samples.

FIPV Ab test is based on the usual situation that the level of feline coronavirus antibodies after the occurrence of feline infectious peritonitis is significantly higher than the expression of common coronavirus antibodies. By detecting the expression of feline coronavirus antibodies, and combined with the clinical situation, it can provide information for veterinarians to comprehensively judge the status of FIPV infection.

Assay Time:  5-10 minutes

Specimen: pleural fluid, ascetic fluid.

¤  TEST PROCEDURE

- Allow all materials, including specimen and test device, recover to 15-25℃ before running the assay.

- Take out the test card from the foil pouch and place it horizontally.

- Use the capillary dropper （10μL）to place 2 drop (approx.20μL) of the ascites or pleural fluid samples into a vial of assay buffer and mix well. Then use the Disposable dropper 3 drops (approx. 90μL) of the diluted sample into the sample hole “S” of the test card.

- Interpret the result in 5-10 minutes. Result after 10 minutes is considered as invalid.

¤  What is FIP?

Feline infectious peritonitis (FIP) is a viral disease of cats caused by certain strains of a virus called the feline coronavirus. Most strains of feline coronavirus are found in the gastrointestinal tract and do not cause significant disease. These are referred to as feline enteric coronavirus (FeCV). Cats infected with FeCV usually do not show any symptoms during the initial viral infection, but may occasionally experience brief bouts of diarrhea and/or mild upper respiratory signs from which they recover spontaneously. FeCV-infected cats usually mount an immune response through which antibodies against the virus are produced within 7-10 days of infection. In approximately 10 percent of cats infected with FeCV, one or more mutations of the virus can alter its biological behavior, resulting in white blood cells becoming infected with virus and spreading it throughout the cat’s body. When this occurs, the virus is referred to as the FIPV. An intense inflammatory reaction to FIPV occurs around vessels in the tissues where these infected cells locate, often in the abdomen, kidney, or brain. It is this interaction between the body’s own immune system and the virus that is responsible for the development of FIP. Once a cat develops clinical FIP, the disease is usually progressive and almost always fatal without therapy that has recently become available, but that has yet to be approved to treat FIP in cats by the Food and Drug Administration (FDA) (see below). To our knowledge, coronaviruses cannot be passed from infected cats to humans.

¤  Is my cat at risk for developing FIP?

Any cat that carries FeCV is potentially at risk for developing FIP, but younger cats are at greater risk of developing FIP, with approximately 70% of cases diagnosed in cats less than 1 1/2 years of age and 50% of cases occurring in cats less than 7 months of age. The most common mode of transmission of FeCV is believed to occur when infected queens pass along the virus to their kittens, usually when the kittens are between five and eight weeks of age. Cats that are housed in high-density facilities (i.e. shelters, catteries) appear to be more susceptible to the development of FIP, as are pure bred cats, male cats, and geriatric cats, for reasons that remain unclear.

J&G Biotech Ltd (Reg. No.: 08419172)

326 Cleveland Road, London, England E18 2AN, UK